Slow Clockreference notes on healthy ageing

Blood pressure

The single most modifiable driver of stroke and heart disease, and the one number most people could know and don't.

settledLarge, consistent evidence base. Unlikely to reverse.Revised 05 Jun 2026

Blood pressure monitor cuff on a table

A home monitor with an upper-arm cuff. Wrist devices are less reliable.Photograph: Hush Naidoo Jade Photography / Unsplash

Definition

The pressure blood exerts on artery walls, written as two numbers: systolic (during the heartbeat) over diastolic (between beats), in millimetres of mercury. Hypertension is conventionally defined as a reading at or above 140/90 mmHg on repeated measurement, though treatment thresholds vary by guideline and by individual risk.

Why it dominates

Raised blood pressure is the leading modifiable risk factor for stroke, ischaemic heart disease, heart failure, chronic kidney disease and vascular cognitive impairment — and it appears in the Lancet Commission’s list of modifiable dementia risk factors as well.

Two features make it unusually important in the context of ageing:

  • It is silent. There are no reliable symptoms until organ damage has occurred. Most people with hypertension do not know.
  • It rises by default. Arterial stiffening with age pushes systolic pressure up across the population, so the question is not whether yours will drift but whether anyone is watching.

What moves it

In rough order of effect for someone in the ordinary range:

Lever Typical effect
Antihypertensive medication Large, reliable, cheap
Weight loss where there is excess weight Several mmHg per few kg
Sodium reduction A few mmHg, more in salt-sensitive people
Regular aerobic exercise A few mmHg, sustained
Reduced alcohol intake Meaningful in heavy drinkers
Potassium-rich diet Modest, additive to sodium reduction

Nothing on the lifestyle side substitutes for medication when pressure is high enough to warrant it. The relationship works the other way: they add.

How to measure it properly

Home monitoring beats a single clinic reading, largely because of white-coat effects. The protocol matters more than the device:

  • Upper-arm cuff, correctly sized. Wrist monitors are less reliable.
  • Sitting, back supported, feet flat, arm at heart height, five minutes still.
  • No coffee or exercise in the preceding half hour.
  • Two readings a minute apart, morning and evening, for several days. Average them. A single reading means very little.

Open questions

How low to push treated pressure in older adults is genuinely contested — intensive targets reduce cardiovascular events but increase falls and kidney events in some groups, and the balance shifts with frailty. That is a decision for a clinician with your history, not a rule.

Sources

  1. WHO — Hypertension (fact sheet)
  2. WHO — Global report on hypertension (2023)
  3. Livingston et al. — Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission